Muscle relaxant less sedating
Although these agents aren’t recommended for long-term use, approximately 44.5% of patients who receive them remain on them for more than a year.Nevertheless, we tend to see cyclobenzaprine prescribed to patients with multiple refills.Efficacy, safety, and cost are the cornerstones of pharmacotherapy and important factors to consider when evaluating medication use and contemplating best therapeutic options.These factors must be considered at therapy initiation and reassessment should be ongoing throughout the course of treatment.
SOURCES: National Sleep Foundation: “Sleepiness, Medication & Drugs: Why Your OTC Medications and Prescription Drugs Might Make You Tired.”National Institute of Mental Health: “Brain Basics.”FDA: “Caution: Some Over-the-Counter Medicines May Affect Your Driving.”National Capital Poison Center: “Antihistamines: Using Them Safely.”Mayo Clinic: “Tricyclic Antidepressants and Tetracyclic Antidepressants.”County of San Mateo Health System: “Benzodiazepines.”American Heart Association: “Types of Blood Pressure Medications.”American Cancer Society: “What Causes Cancer-related Fatigue?
This article was collaboratively written with Mena Raouf, Pham D. Raouf received his Pharm D from Albany College of Pharmacy and Health Sciences, with a concentration in nephrology. Amrix (cyclobenzaprine hydrochloride) capsule, extended release [package insert].
He is currently pursuing a PGY-1 pharmacy practice residency at the VA Tennessee Valley Healthcare System.. North Wales, PA: Teva Pharmaceuticals USA, Inc.; 2013 Jun.
Furthermore, when used in patients receiving opioid therapy, cyclobenzaprine and other CNS depressants potentiate the risk for opioid-induced respiratory depression. Muscle relaxants for nonspecific low back pain: a systematic review within the framework of the Cochrane Collaboration.
Therefore, it’s important to counsel patients on opioids who present a prescription for cyclobenzaprine, or better yet, call the prescriber and share your knowledge.